NF- B Family of Transcription Factors: Central Regulators of Innate and Adaptive Immune Functions
نویسندگان
چکیده
INTRODUCTION .......................................................................................................................................................414 NFB AND REGULATION OF THE IMMUNE SYSTEM ................................................................................415 Proand Antiapoptotic Functions of NFB ......................................................................................................415 Development ............................................................................................................................................................416 Homeostasis and Lymphoid Architecture ...........................................................................................................416 Innate Immunity .....................................................................................................................................................417 T-Cell Activation and Effector Function..............................................................................................................418 B-Cell Activation and Effector Function..............................................................................................................419 NFB AND INFECTION .........................................................................................................................................420 Resistance and Susceptibility to Pathogens........................................................................................................420 NFB and the Host-Pathogen Relationship ......................................................................................................421 HUMAN DISEASE AND NFB ..............................................................................................................................422 CONCLUSIONS .........................................................................................................................................................423 ACKNOWLEDGMENTS ...........................................................................................................................................424 REFERENCES ............................................................................................................................................................424
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NF-kappaB family of transcription factors: central regulators of innate and adaptive immune functions.
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